Publications
Weis VG, Deal AC, Mekkey G, Clouse C, Gaffley M, Whitaker E, Peeler CB, Weis JA, Schwartz MZ, Atala A. Human placental-derived stem cell therapy ameliorates experimental necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1;320(4):G658-G674. doi: 10.1152/ajpgi.00369.2020. Epub 2021 Feb 10. PubMed PMID: 33566727; PubMed Central PMCID: PMC8238163.
Engevik AC, Krystofiak ES, Kaji I, Meyer AR, Weis VG, Goldstein A, Coutts AW, Melkamu T, Saqui-Salces M, Goldenring JR. Recruitment of Polarity Complexes and Tight Junction Proteins to the Site of Apical Bulk Endocytosis. Cell Mol Gastroenterol Hepatol. 2021;12(1):59-80. doi: 10.1016/j.jcmgh.2021.01.022. Epub 2021 Feb 3. PubMed PMID: 33548596; PubMed Central PMCID: PMC8082271.
Weis VG, Deal AC, Mekkey G, Clouse C, Gaffley M, Whitaker E, Weis JA, Schwartz MZ, Atala A. Human placental-derived stem cell therapy ameliorates experimental necrotizing enterocolitis and supports restoration of the intestinal stem cell niche. [preprint]. 2020 October. Available from: https://doi.org/10.1101/2020.10.05.327437. doi: https://doi.org/10.1101/2020.10.05.327437.
Engevik AC, Kaji I, Engevik MA, Meyer AR, Weis VG, Goldstein A, Hess MW, Müller T, Koepsell H, Dudeja PK, Tyska M, Huber LA, Shub MD, Ameen N, Goldenring JR. Loss of MYO5B Leads to Reductions in Na+ Absorption With Maintenance of CFTR-Dependent Cl- Secretion in Enterocytes. Gastroenterology. 2018 Dec;155(6):1883-1897.e10. doi: 10.1053/j.gastro.2018.08.025. Epub 2018 Aug 23. PubMed PMID: 30144427; PubMed Central PMCID: PMC6279525.
Schlegel C, Lapierre LA, Weis VG, Williams JA, Kaji I, Pinzon-Guzman C, Prasad N, Boone B, Jones A, Correa H, Levy SE, Han X, Wang M, Thomsen K, Acra S, Goldenring JR. Reversible deficits in apical transporter trafficking associated with deficiency in diacylglycerol acyltransferase. Traffic. 2018 Nov;19(11):879-892. doi: 10.1111/tra.12608. Epub 2018 Sep 21. PubMed PMID: 30095213; PubMed Central PMCID: PMC6191315.
Schlegel C, Weis VG, Knowles BC, Lapierre LA, Martin MG, Dickman P, Goldenring JR, Shub MD. Apical Membrane Alterations in Non-intestinal Organs in Microvillus Inclusion Disease. Dig Dis Sci. 2018 Feb;63(2):356-365. doi: 10.1007/s10620-017-4867-5. Epub 2017 Dec 7. PubMed PMID: 29218485; PubMed Central PMCID: PMC5797493.
Weis VG, Petersen CP, Weis JA, Meyer AR, Choi E, Mills JC, Goldenring JR. Maturity and age influence chief cell ability to transdifferentiate into metaplasia. Am J Physiol Gastrointest Liver Physiol. 2017 Jan 1;312(1):G67-G76. doi: 10.1152/ajpgi.00326.2016. Epub 2016 Nov 23. PubMed PMID: 27881402; PubMed Central PMCID: PMC5283902.
Weis VG, Knowles BC, Choi E, Goldstein AE, Williams JA, Manning EH, Roland JT, Lapierre LA, Goldenring JR. Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum. Cell Mol Gastroenterol Hepatol. 2016 Feb 1;2(2):131-157. doi: 10.1016/j.jcmgh.2015.11.009. PubMed PMID: 27019864; PubMed Central PMCID: PMC4806369.
Choi E, Petersen CP, Lapierre LA, Williams JA, Weis VG, Goldenring JR, Nam KT. Dynamic expansion of gastric mucosal doublecortin-like kinase 1-expressing cells in response to parietal cell loss is regulated by gastrin. Am J Pathol. 2015 Aug;185(8):2219-31. doi: 10.1016/j.ajpath.2015.04.009. Epub 2015 Jun 12. PubMed PMID: 26073039; PubMed Central PMCID: PMC4530133.
Knowles BC, Weis VG, Yu S, Roland JT, Williams JA, Alvarado GS, Lapierre LA, Shub MD, Gao N, Goldenring JR. Rab11a regulates syntaxin 3 localization and microvillus assembly in enterocytes. J Cell Sci. 2015 Apr 15;128(8):1617-26. doi: 10.1242/jcs.163303. Epub 2015 Feb 11. PubMed PMID: 25673875; PubMed Central PMCID: PMC4518445.
Weis VG, Petersen CP, Mills JC, Tuma PL, Whitehead RH, Goldenring JR. Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15;307(8):G777-92. doi: 10.1152/ajpgi.00169.2014. Epub 2014 Sep 4. PubMed PMID: 25190476; PubMed Central PMCID: PMC4200317.
Petersen CP, Weis VG, Nam KT, Sousa JF, Fingleton B, Goldenring JR. Macrophages promote progression of spasmolytic polypeptide-expressing metaplasia after acute loss of parietal cells. Gastroenterology. 2014 Jun;146(7):1727-38.e8. doi: 10.1053/j.gastro.2014.02.007. Epub 2014 Feb 15. PubMed PMID: 24534633; PubMed Central PMCID: PMC4035414.
Weis VG, Sousa JF, LaFleur BJ, Nam KT, Weis JA, Finke PE, Ameen NA, Fox JG, Goldenring JR. Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression. Gut. 2013 Sep;62(9):1270-9. doi: 10.1136/gutjnl-2012-302401. Epub 2012 Jul 7. PubMed PMID: 22773549; PubMed Central PMCID: PMC3762676.
Geahlen JH, Lapid C, Thorell K, Nikolskiy I, Huh WJ, Oates EL, Lennerz JK, Tian X, Weis VG, Khurana SS, Lundin SB, Templeton AR, Mills JC. Evolution of the human gastrokine locus and confounding factors regarding the pseudogenicity of GKN3. Physiol Genomics. 2013 Aug 1;45(15):667-83. doi: 10.1152/physiolgenomics.00169.2012. Epub 2013 May 28. PubMed PMID: 23715263; PubMed Central PMCID: PMC3742967.
Nam KT, Lee HJ, Sousa JF, Weis VG, O'Neal RL, Finke PE, Romero-Gallo J, Shi G, Mills JC, Peek RM Jr, Konieczny SF, Goldenring JR. Mature chief cells are cryptic progenitors for metaplasia in the stomach. Gastroenterology. 2010 Dec;139(6):2028-2037.e9. doi: 10.1053/j.gastro.2010.09.005. Epub 2010 Sep 18. PubMed PMID: 20854822; PubMed Central PMCID: PMC2997152.
Weis VG, Goldenring JR. Current understanding of SPEM and its standing in the preneoplastic process. Gastric Cancer. 2009;12(4):189-97. doi: 10.1007/s10120-009-0527-6. Epub 2010 Jan 5. Review. PubMed PMID: 20047123; PubMed Central PMCID: PMC4502916.
Nozaki K, Weis V, Wang TC, Falus A, Goldenring JR. Altered gastric chief cell lineage differentiation in histamine-deficient mice. Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1211-20. doi: 10.1152/ajpgi.90643.2008. Epub 2009 Apr 9. PubMed PMID: 19359424; PubMed Central PMCID: PMC2697940.
Bredemeyer AJ, Geahlen JH, Weis VG, Huh WJ, Zinselmeyer BH, Srivatsan S, Miller MJ, Shaw AS, Mills JC. The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage. Dev Biol. 2009 Jan 1;325(1):211-24. doi: 10.1016/j.ydbio.2008.10.025. Epub 2008 Oct 31. PubMed PMID: 19013146; PubMed Central PMCID: PMC2634829.
Ramsey VG, Doherty JM, Chen CC, Stappenbeck TS, Konieczny SF, Mills JC. The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1. Development. 2007 Jan;134(1):211-22. doi: 10.1242/dev.02700. PubMed PMID: 17164426; NIHMSID:NIHMS467383.